High-shear mixer granulator
Mixing solutions for pharmaceutical granulation
High-shear mixer granulator
DIOSNA high-shear mixer granulators are designed for precise mixing and wet granulation, and pelletizing in pharmaceutical R&D, pilot, and production environments. These high-shear mixer granulator ensures reproducible granule quality, great API and particle size distribution, homogeneity, and scalable performance from laboratory trials to full-scale manufacturing.
Benefits:
- Wet and hotmelt granulation
- Pellet production with optional spheronizer
- Pilot plant testing and clinical sample preparation
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DIOSNA high-shear mixer-granulators provide laboratories, pilot plants, and production facilities with precise and reproducible mixing, granulation, and pelletizing. Designed for flexibility and high performance, these mixers ensure optimal API distribution, particle homogeneity, and scalable process results.
Laboratory and pilot performance with flexible operation
These mixers allow controlled and reproducible processing for small to medium batches, ideal for R&D, formulation testing, and clinical sample preparation. Operators can choose from multiple bowl sizes and mixing/granulation modes, enabling customized testing and scale-up to production volumes. Mobile or tabletop units provide ergonomic handling and tool-free bowl changes for easy capacity adjustment.
Hygiene and operator-friendly design
All units feature cylindrical-conical vessels, chopper tools for optimal granulation, and easy-to-clean surfaces. The system supports solvent-based operations, and containment solutions. Integrated touchpad or PLC control ensures precise monitoring of mixing, granulation, and pelletizing parameters.
Precision control and automation
Freely programmable parameters and modular design enable reproducible results batch after batch. Optional spheronizer, peristaltic pumps, and CIP-capable components extend functionality and simplify cleaning, making these mixers ideal for laboratories and production plants focused on product development, scale-up, and consistent quality.
| Model | Bowl size | Batch size | Ideal for | |
|---|---|---|---|---|
| P1-6 | 0.25 – 6 L | 0.04 – 2.7 kg | R&D, small batch testing, pilot lab work | |
| P/VAC-10 | P: 0.25–10 L VAC: 2, 6, 10 L | Lab-scale granulation and drying, flexible R&D work | ||
| P/VAC 10-60 | P: 10–60 L VAC: 20, 50 L | Pilot plant trials, clinical sample prep, small production runs | ||
| P100 | 120 L | Small to medium | Start-up production, small-scale pharmaceutical batches | |
| P250-1250 | Customizable (250–1250 L) | Large batches | Full-scale pharmaceutical production, high-volume granulation & pelletizing | |
P1-6 – the compact and efficient laboratory mixer
P/VAC-10 – the powerful and maximally flexible laboratory unit
P/VAC 10-60 – pilot single-pot processor with full benefits
P100 – the reliable mixer-granulator for your production start-up
P250-1250 – Production scale pharmaceutical mixer
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